Getting “dumber” as we age may be explained (in part) by changes in neuronal sodium channel function The hippocampus is heavily involved in cognition. It’s one of the first areas of the brain to show signs of damage characteristic of Alzheimer’s disease. A Pfizer-sponsored team at the University of Bristol (England) used the patch clamp [...]
Categories: Neuroscience
Tagged: age-related, aging, Andrew D. Randall, brain, Clair Booth, gating, hippocampal CA1 pyramidal, hippocampus, hypoexcitability, Jon T. Brown, mice, Na+, neuronal, Pfizer, sodium channels, University of Bristol