Tag Archives: E. coli

Carbapenem-resistant Enterobacteriaceae bacterial infections are on the rise — not so good news, given that mortality is 40 percent among those whose infections transition into septicemia 0

© 2013 Peter Free Citation — to study Morbidity and Mortality Weekly Report (MMWR), Vital Signs: Carbapenem-Resistant Enterobacteriaceae, Centers for Disease Control and Prevention (05 March 2013) What are carbapenems? Carbapenems are a class of antibiotic that were invented to attack bacteria that had evolved resistance to other “beta-lactam” antibiotics, like penicillin. Note “Beta-lactam” refers [...]

Replicating bacteria may divide aged from newer intra-cellular components, thereby creating one fitter and one less fit offspring — this is evolutionarily more favorable than giving both daughters equal amounts of garbage 0

An inference from computer theory and subsequent visual analysis Given the way bacteria split, we once thought that they didn’t really age.  This now appears not to be true.  From an evolutionary perspective, it would make sense to put accumulated non-genetic damage into one offspring and the newer materials in the other. A University of [...]

Developing better ways to study the evolution of antimicrobial resistance — using microfluidic devices and dynamic concentration gradients 0

Conceptual background — drug concentration gradients and bacterial niches within the body One relatively obvious aspect of antibiotic resistance is that the body has physically and temporally- gradated drug concentration zones.  “Niches” vary in their chemical qualities across time. Where antibiotic concentrations are high, sensitive bacteria are killed — which means that they are much [...]

A type of kinship selection demonstrated in bacteria ─ their clan against ours 0

Subtleties in natural selection go beyond simple “survival of the fittest” Altruistic behavior in human beings has been the subject of evolutionary study for some time.  A form of the same has been discovered in Escherichia coli: Here we follow a continuous culture of Escherichia coli facing increasing levels of antibiotic and show that the [...]