Biochemistry in action A study of 450 osteoarthritis patients revealed that the chemistry of extracellular (joint) proteins works differently in hips versus knees. The study, according its authors, seems to indicate that deamidation of asparagine into aspartic acid is at work in both joints, but the damage is continually repaired in knees. Citation Jonathan B. [...]
Categories: Medicine
Tagged: amide group, artilage oligomeric matrix protein, asparagine, aspartic acid, Christopher R. McCudden, deamidation, hip, Joanne M. Jordan, Jonathan B. Catterall, Jordan B. Renner, knee, matrix turnover, Michael Bolognesi, Ming F. Hsueh, OA, osteoarthritis, Robert Zura, Sheng Feng, Thomas V. Stabler, Virginia B. Kraus